The gameboard is a 10x10 grid, numbered from 1-12 in four different colors (brown, orange, red, and green). The center four squares are marked "Skip." A deck of PHASE 10 cards and plastic chips in three colors are also provided.

Players play cards that allow them to place a chip on a square that matches the card's color/number combination. Players attempt in this way to place five of their chips in a horizontal, vertical, or diagonal row. "Skip" cards allow the player to place a chip on one of the matching center squares, and cause the following player to miss the next turn. Wild cards are also included.